Searchable abstracts of presentations at key conferences in endocrinology

ea0092op-10-01 | Oral Session 10: Novel diagnostics in Thyroid cancer | ETA2023

Identification of clinical and histopathological risk factors for radioactive iodine refractory disease in patients with follicular and hurthle cell thyroid carcinoma

Stegenga Merel , Oudijk Lindsey , Van Velsen Evert , Medici Marco , Peeters Robin , Edward Visser W. , van Kemenade Folkert

Introduction: Historically, treatment of follicular thyroid carcinoma (FTC) and oncocytic thyroid carcinoma (OTC) is based on thyroidectomy followed by radioiodine (RAI) therapy. Both tumor types have a good prognosis (10-year survival 80-94%), but this changes significantly once RAI-refractory disease occurs (median 3.5 years), which limits further treatment possibilities. The main risk factors for developing RAI-refractory disease in FTC and OTC are unknown. Our aim was to i...